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Ce n'est pas une liste complète de toutes les interactions qui peuvent se produire. That said, there are some lines that shouldn't be crossed.
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Mitochondrial inhibition by metformin causes energetic stress, diclofenac hexa 50 mg which results in activation of the energy sensor adenosine monophosphate-activated protein kinase (AMPK) ( Zhou et al., 2001 x Role of AMP-activated protein kinase in mechanism of metformin action.